Peptide purification
WorkBeads 40S is an excellent tool for purification of therapeutic peptides from crude feeds following solid-phase synthesis or after recombinant expression
Cation exchange chromatography is a useful technique for purification of many peptides. The use of cation exchange resins to purify crude feeds following solid-phase synthesis or after recombinant expression can extend the lifetime of reverse phase chromatography (RPC) resins and/or reduce the use of organic solvents in downstream purification.
WorkBeads 40S, an agarose-based cation exchange resin, has proven to be an excellent tool for purification of therapeutic peptides due to its high binding capacity and optimal flow pressure properties. WorkBeads 40S results in high purity without compromising yield.

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Whitepaper
IEX and RPC compatibility in peptide purifications: a generic procedure for implementing IEX upstream of RPC
Poster
Increased lifetime of RPC resins in insulin production by clean-up using WorkBeads 40S
Application note
glycopeptide conjugate API purification