Bio-Works provides cutting-edge, proprietary agarose-based resins for purification of biomolecules
Bio-Works is the home of WorkBeadsTM chromatography resins for purification of mAbs, proteins, peptides, oligos, viruses and vaccines. WorkBeads resins have a unique composition of porous beads with tight bead- and pore-size distribution giving outstanding purity, high binding capacity and high flow rates. They’re used in small-scale research projects or large-scale industrial production. The site for production, development and sales is located in Uppsala, Sweden and Bio-Works quality management system is certified according to ISO 9001.
Bio-Works was founded in 2006 by four leaders in protein purification and has grown rapidly. We have as much passion for chromatographic purification as we have experience in this field.
Our mission & vision
Our mission is to make important medicines available and accessible to everyone.
We envision a biotech industry that embraces, develops and builds on new methods and novel ideas. A marketplace that better serves science, utilises resources more effectively, and which better meets the different needs of all involved parties.
Quality management system
Our products stand out as innovative and cutting edge with exceptional performance
Proteins for example, but also many other biomolecules, can be purified from complex mixtures in sample solutions using liquid chromatography. Small beads of a highly rigid adsorber beads (made of agarose) are packed into a column. The beads are designed to selectively bind the protein under specific chemical conditions.
The sample solution is pumped through the column, and the protein of interest binds to the beads. The rest of the sample is washed through the column. To then recover the protein, a solution of different pH or ionic strength is passed through the column. The protein releases from the bead and is washed from the column and collected.
A similar approach is used to separate molecules based on size in which the physical structure of the beads allows certain sized molecules to pass through or be retained by the column. The beads can also be coated with various substances which will specifically bind a molecule of interest, allowing it to be separated from other molecules and purified or concentrated.
From Uppsala to the world
Our team of "Bio-Workers"
Our next generation resins, WorkBeads,™ vary in agarose content, size range of beads and pore size. Through our patented manufacturing process we are able to offer high quality agarose-based resins which allow higher flow rates and better capacity than traditional resins. The result for our customers is lower total production costs and better process reliability.