Viruses and vaccine purification
WorkBeads 40/100, 40/1000 and 40/10 000 SEC are a gentle method for purifying vaccines and viruses and different buffers and pH can easily be used
Size exclusion chromatography is a separation technique that is very useful when purifying vaccines and viruses. The method is gentle towards the target molecules and different buffers and pH can easily be used. The vaccine or virus will pass through the column and elute earlier compared to smaller impurities.
Preparative virus purifications are often based on various filtration, precipitation, or ultracentrifugation techniques. None of these techniques are automated and they require time-consuming manual handling. There is a clear need for more efficient approaches for virus downstream processing. Chromatography is an alternative that offers automated and affordable purifications. WorkBeads SEC resins produce purified virus at high yield and with high activity.

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Poster
Purification of animal viral vaccine from cell supernatants by size exclusion chromatography