Ten things you must know when producing synthetic therapeutic peptides
Peptide therapeutic agents are enjoying increasing success but they are challenging to produce and, not [...]
QuickTip #4: yield of His-tagged proteins
Immobilized Metal Ion Affinity Chromatography (IMAC) is used for purification of His-tagged proteins. Ni-NTA based [...]
Join the effort to make chromatography sustainable
The environmental impact of pharmaceutical R&D and production is considerable. Although the industry is rather [...]
QuickTip #3: optimizing mAb purification
Designing an optimized purification process means maximizing yield and purity, and at the same time [...]
Affordable and safe biosimilars for affordable healthcare
When it comes to many serious and challenging diseases, healthcare has reached a point of [...]
Are mAbs the ultimate targeted therapy?
Since the 1980’s, monoclonal antibodies (mAbs) have revolutionized healthcare and continue to do so. A [...]
QuickTip #2: choosing IEX resin
Recovery of your biologically active target substance is a priority, and it’s important to check for [...]
CHO cells in fed-batch bioreactors dominate mAb upstream processes
Choosing a mammalian cell line or other type of host is as critical a question [...]
QuickTip #1: cleaning IEX columns
When an IEX resin has been used for some time, impurities may build up in [...]
Illnesses with approved monoclonal antibody therapies
As our understanding of diseases at the molecular level increases, so does the potential for [...]
