Blog

Trends and know-how in biotech and downstream purification.

Traditional Chinese medicine: Separation techniques that improve efficacy

Traditional Chinese medicine (TCM) is an ancient traditional medical system that has developed over thousands of years in China without recorded external influence. TCM includes various treatment...

Current trends in Advanced Therapeutic Medicinal Products (ATMPs)

Advanced therapy medicinal products (ATMPs) are human therapeutics that are based on genes, tissues or cells. They offer groundbreaking new opportunities for the treatment of disease. In many ways,...

How to improve peptide purification for affordable insulin

The global diabetes pandemic has created a massive demand for insulin, especially in China, which is expected to have half the world’s diabetes patients soon. Meeting this demand means developing...

How reversing downstream bioprocess steps can make all the difference

Improving the downstream bioprocess economy depends on fine-tuning an enormous range of parameters, from culture and harvesting to purification and final polishing. Success depends on the ability to...

How diversity in peptide therapeutics can revolutionize medicine

More than 80 peptide drugs have been approved by the FDA so far, and many more are in clinical development for a wide range of diseases. Peptide drugs have substantial therapeutic potential because...

How to improve process efficiency and economy in peptide production

The purity requirements for therapeutic peptides are very stringent, but synthesis generates a crude peptide mixture containing failed sequences and chemical variants, while recombinant peptides have...

The promise and the price of the new biopharmaceuticals

The healthcare sector and developers of new pharmaceuticals are facing increasing challenges, along with pressure to lower costs. At the same time pharmaceutical development is undergoing a...

Advances in oligonucleotide therapeutics by molecular diversity

Therapeutic oligonucleotides are relatively simple molecules in the world of molecular biology. They are single- or double-stranded segments of DNA or RNA of about 10–50 nucleotides. Yet, despite...

New biopharmaceuticals on the horizon: A purification challenge

In 1982 a new type of pharmaceutical appeared on the market. Recombinant human insulin was approved for human therapeutic use and is generally acknowledged as the first “biopharmaceutical” or...

How prepacked chromatography columns help you scale up biomanufacturing faster

Chromatography is a popular purification technique used in biomanufacturing to separate and isolate your target biomolecule from the presence of impurities. To scale up the biomanufacturing process...