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Trends and know-how in biotech and downstream purification.

Optimized purification of antibodies using a new high-capacity and alkaline stable protein A resin

Introduction A new protein A chromatography resin has been designed for purification of mAbs, Gabs and polyclonal antibodies. The new resin, WorkBeads™ affimAb, is designed for high dynamic binding...

Efficient protection of protein A resins during mAb purifications

Introduction The purity requirements are high for monoclonal antibodies (mAbs). Using protein A chromatography resins result in mAbs with high yield and purity in a single step and is therefore the...

A novel protein A-based resin for optimized purification of antibodies

Introduction A protein A ligand designed to give high alkaline stability was immobilized on WorkBeads™ basematrix. The combination of ligand concentration and resin properties was optimized for high...