Blog

Trends and know-how in biotech and downstream purification.

Current trends in Advanced Therapeutic Medicinal Products (ATMPs)

Advanced therapy medicinal products (ATMPs) are human therapeutics that are based on genes, tissues or cells. They offer groundbreaking new opportunities for the treatment of disease. In many ways,...

How to improve peptide purification for affordable insulin

The global diabetes pandemic has created a massive demand for insulin, especially in China, which is expected to have half the world’s diabetes patients soon. Meeting this demand means developing...

How reversing downstream bioprocess steps can make all the difference

Improving the downstream bioprocess economy depends on fine-tuning an enormous range of parameters, from culture and harvesting to purification and final polishing. Success depends on the ability to...

How to improve process efficiency and economy in peptide production

The purity requirements for therapeutic peptides are very stringent, but synthesis generates a crude peptide mixture containing failed sequences and chemical variants, while recombinant peptides have...

The promise and the price of the new biopharmaceuticals

The healthcare sector and developers of new pharmaceuticals are facing increasing challenges, along with pressure to lower costs. At the same time pharmaceutical development is undergoing a...

Advances in oligonucleotide therapeutics by molecular diversity

Therapeutic oligonucleotides are relatively simple molecules in the world of molecular biology. They are single- or double-stranded segments of DNA or RNA of about 10–50 nucleotides. Yet, despite...

New biopharmaceuticals on the horizon: A purification challenge

In 1982 a new type of pharmaceutical appeared on the market. Recombinant human insulin was approved for human therapeutic use and is generally acknowledged as the first “biopharmaceutical” or...

How prepacked chromatography columns help you scale up biomanufacturing effectively

Chromatography is a popular purification technique used in biomanufacturing to separate and isolate your target biomolecule from the presence of impurities. To scale up the biomanufacturing process...

Pharma 4.0: Revolutionizing the Pharmaceutical Industry

Pharma 4.0, the latest buzzword in the pharmaceutical industry, has the potential to transform the industry by making the drug development process faster, more efficient, and more patient-centric. By...

Interview with Ryan MacDougall of Lonza

At BPI in Boston this September we were lucky enough to get to talk to Ryan MacDougall of Lonza and to hear about the BioPhorum group that he was representing at the conference.